Search results for "stress depression"

showing 2 items of 2 documents

Lasting downregulation of the lipid peroxidation enzymes in the prefrontal cortex of mice susceptible to stress-induced anhedonia

2015

International audience; Antioxidant enzymes and lipid peroxidation in the brain are involved in neuropsychiatric pathologies, including depression. 14- or 28-day chronic stress model induced a depressive syndrome defined by lowered reward sensitivity in C57BL/6J mice and changed gene expression of peroxidation enzymes as shown in microarray assays. We studied how susceptibility or resilience to anhedonia is related to lipid peroxidation in the prefrontal cortex (PFC). With 14-day stress, a comparison of the activities of catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPX) and accumulation of malondialdehyde (MDA) revealed a decrease of the first two measures in suscepti…

Malemedicine.medical_specialtyImipramineAnhedoniaLipid peroxidationDown-RegulationMotor ActivityMicroarrayHippocampusImipraminePrefrontal cortexGene Expression Regulation EnzymologicSuperoxide dismutaseLipid peroxidationFood PreferencesMiceBehavioral Neurosciencechemistry.chemical_compoundNeurochemicalMalondialdehydeInternal medicinemedicineAnimalsChronic stresschemistry.chemical_classificationGlutathione PeroxidasebiologySuperoxide Dismutasebusiness.industryGene Expression ProfilingGlutathione peroxidaseAnhedoniaResilience PsychologicalCatalaseMalondialdehydeAggressionEndocrinologychemistrybiology.protein[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]medicine.symptombusinessChronic stress depression modelStress Psychologicalmedicine.drug
researchProduct

Pre-sleep arousal and sleep quality during the COVID-19 lockdown in Italy

2021

Abstract Objective The COVID-19 pandemic has strongly affected daily habits and psychological wellbeing, and many studies point to large modifications in several sleep and sleep-related domains. Nevertheless, pre-sleep arousal during the pandemic has been substantially overlooked. Since hyperarousal represents one of the main factors for the development and the perpetuation of chronic insomnia disorder, the assessment of variables associated with high levels of pre-sleep arousal during the pandemic is clinically relevant. The study aimed to assess the prevalence and predictors of perceived sleep quality and pre-sleep arousal in an Italian sample during the COVID-19 lockdown. Methods We used…

stress depressionCOVID-19 pandemic; Depression; Pre-sleep arousal; Sleep quality; Stress.Coronavirus disease 2019 (COVID-19)Pre sleep arousalStreSocio-culturaleCOVID-19 pandemicSettore MED/10 - Malattie Dell'Apparato RespiratorioStressArousalCOVID-19 pandemic; Depression; Pre-sleep arousal; Sleep quality; Stress; Arousal; Communicable Disease Control; Humans; Pandemics; SARS-CoV-2; Sleep; Sleep Quality; Surveys and Questionnaires; COVID-19; Sleep Initiation and Maintenance DisordersSurveys and QuestionnairesSleep Initiation and Maintenance DisordersInsomniamedicineHumansSurveys and QuestionnairePandemicsPre-sleep arousalDepression (differential diagnoses)Sleep qualityPandemicbusiness.industryDepressionSARS-CoV-2COVID-19CognitionGeneral MedicineSleep qualitySleep in non-human animalsCOVID-19 pandemic; sleep quality; pre-sleep arousal; stress depressionCommunicable Disease ControlOriginal Articlemedicine.symptombusinessArousalSleepClinical psychologyHuman
researchProduct